Citalopram is used for treating depression.
Escitalopram generic availability data, January 2014 through December 2015, show the generic rate for aripiprazole being nearly the same as for duloxetine at about $75 a 120-day supply, approximately the same as for other selective serotonin reuptake inhibitors.6,8
Aripiprazole for Depression: Current Clinical Development
It has been widely reported that aripiprazole is considered to be a positive first-line antidepressant,7,10 with improvements being noted within 6 weeks of starting administration.11,12
Aripiprazole has also been shown to decrease the antidepressant-refractory course of major depression, a condition that is characterized by profound, persistent negative symptoms that cannot be adequately treated with psychotherapy or other established agents.13-14 As demonstrated in a series of double-blind, placebo-controlled trials, aripiprazole produced a significant reduction in the number of patients who experienced a relapse after adequate antidepressant therapy was withdrawn.15 Aripiprazole showed a similar efficacy in an open-label, multicenter trial by the German agency for pharmaceutical regulatory medicine, including 14 major depressive episode trials, with at least one-third of participants randomized to aripiprazole.16
Aripiprazole, however, has not been approved for the treatment of depressive disorder; neither the United States Food and Drug Administration nor the European Medicines Agency has approved aripiprazole for treatment of depression.18 The manufacturer also indicates that aripiprazole therapy has been used for treating anxiety, but this is not supported by published research.19
Aripiprazole is not a high-risk, first-line agent for the treatment of any psychiatric condition.20 Due to clinical experience with aripiprazole, one recent publication suggested that the drug may help to prevent relapse from alcohol dependence, and possibly also bipolar disorder.21 Another, more recent publication suggests that aripiprazole might be effective at improving mental state in Citalopram 40mg $70.94 - $2.36 Per pill patients with bipolar depression, and possibly preventing recurrence of depressive episodes.22
Aripiprazole has been shown, in placebo-controlled trials for major depression, to have a superior pharmacodynamic profile (ie, greater peak and longer duration) than duloxetine, another first-line antidepressant.14 Aripiprazole is well tolerated, with no serious adverse event reports documented in the medical literature.20 For this reason, aripiprazole might also be more suitable for escitalopram generic health early or transition patients when alternative antidepressants are not recommended for their condition and when alternative symptoms are predominant.
Possible Side Effects of Aripiprazole
Aripiprazole is known to have a number of Where to buy proventil inhaler online potentially serious side effects: gastrointestinal disturbances, including nausea, vomiting, diarrhea, abdominal cramps, diarrhea or constipation,6,7,8,12,13,14,15 low-grade fever, and upper respiratory infection, particularly those associated with infection related to streptococcal or methicillin-resistant Staphylococcus pneumoniae.11 Aripiprazole has not been assessed in relation to the frequency or severity of these adverse effects. Aripiprazole should not be used in pregnancy without regard for contraindications (eg, a prior history of pregnancy complications or infection).23,24 The mechanism of action aripiprazole for these side effects has not been determined. For side effects not reported aripiprazole, it is difficult to predict the extent of side effects on such a drug. Aripiprazole does not cause significant increase in cardiovascular medication levels during use.
The drug is unlikely to cause the gastrointestinal symptoms described in patients taking some antidepressant medications,25 although the risks of gastrointestinal bleeding from taking antidepressant drugs, us online pharmacy with prescription as well.
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